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标题：Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus?
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作者：Camille Dugas ; Mélissa Bélanger ; Julie Perron 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2019
卷号：11
期号：3
页码：570-582
DOI：10.3390/nu11030570
出版社：MDPI Publishing
摘要：Children born from mothers with gestational diabetes mellitus (GDM) are at high-risk of obesity and type 2 diabetes. To date, there is a lack of effective strategies to prevent these complications. The aim of this study was to evaluate the association between diet quality and anthropometric and glycemic profiles of children exposed (GDM ) and unexposed (GDM–) to GDM. A total of 104 GDM and 38 GDM– children were included. Two 24-h dietary recall questionnaires were used to assess dietary intakes. The Healthy Eating Index adapted for the Canadian population (HEI-C) was used to assess diet quality. Spearman correlations adjusted for children’s age and sex were computed. Mean age was 6.0 ± 2.5 and 6.8 ± 2.3 years for GDM and GDM–, respectively (p = 0.03). Total HEI-C score was negatively associated with the android-to-gynoid fat mass ratio (r = −0.29, p = 0.03) and homeostasis model assessment for insulin resistance (HOMA-IR) index (r = −0.22, p = 0.04) in GDM children only. The prevalence of being overweight or obese during childhood was 4-fold higher among GDM children with a HEI-C score ≤70 compared to GDM children with a HEI-C score >70. Results of this study show that a healthy diet is associated with a better cardiometabolic health profile in GDM children, including a lower risk of being overweight or obese.
关键词：gestational diabetes; healthy diet; obesity; type 2 diabetes gestational diabetes ; healthy diet ; obesity ; type 2 diabetes