文章基本信息

标题：Exploring the Science behind Bifidobacterium breve M-16V in Infant Health
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作者：Chyn Boon Wong ; Noriyuki Iwabuchi ; Jin-zhong Xiao 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2019
卷号：11
期号：8
页码：1724-1747
DOI：10.3390/nu11081724
出版社：MDPI Publishing
摘要：Probiotics intervention has been proposed as a feasible preventative approach against adverse health-related complications in infants. Nevertheless, the umbrella concept of probiotics has led to a massive application of probiotics in a range of products for promoting infant health, for which the strain-specificity, safety and efficacy findings associated with a specific probiotics strain are not clearly defined. Bifidobacterium breve M-16V is a commonly used probiotic strain in infants. M-16V has been demonstrated to offer potential in protecting infants from developing the devastating necrotising enterocolitis (NEC) and allergic diseases. This review comprehends the potential beneficial effects of M-16V on infant health particularly in the prevention and treatment of premature birth complications and immune-mediated disorders in infants. Mechanistic studies supporting the use of M-16V implicated that M-16V is capable of promoting early gut microbial colonisation and may be involved in the regulation of immune balance and inflammatory response to protect high-risk infants from NEC and allergies. Summarised information on M-16V has provided conceptual proof of the use of M-16V as a potential probiotics candidate aimed at promoting infant health, particularly in the vulnerable preterm population.
关键词：Bifidobacterium breve M-16V; infant health; clinical efficacy; probiotics; gut microbiota Bifidobacterium breve M-16V ; infant health ; clinical efficacy ; probiotics ; gut microbiota