文章基本信息

标题：Influence of Bioactive Nutrients on the Atherosclerotic Process: A Review
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作者：Rosa Casas ; Ramon Estruch ; Emilio Sacanella 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2018
卷号：10
期号：11
页码：1630-1655
DOI：10.3390/nu10111630
出版社：MDPI Publishing
摘要：The protective effects of a dietary intervention as a useful tool in the prevention of atherosclerosis disease has gained greater attention in recent years. Several epidemiological studies have demonstrated the importance of diet in reducing expensive treatments or possible undesirable side effects. The main aim of this review is to examine the effects of specific nutrients on the development and progression of atherosclerosis in patients with cardiovascular disease. Various mechanisms have been proposed to explain the cardioprotective effect of different nutrients. In this sense, results have shown stabilization of vulnerable atherosclerotic plaques or downregulation of biomarkers related to inflammation through nutrients such as Omega-3 polyunsaturated fatty acids, hydroxytyrosol of extra virgin olive oil, lycopen, phytosterols of plants, or flavonols of fruits and vegetables, among others. The accumulated evidence on the anti-inflammatory effects related to these nutrients is summarized in the present review.
关键词：CVD; atherosclerosis; hydroxytyrosol; inflammation; nutrients; polyphenols; PUFA; bioactive compounds; phytosterols CVD ; atherosclerosis ; hydroxytyrosol ; inflammation ; nutrients ; polyphenols ; PUFA ; bioactive compounds ; phytosterols