文章基本信息

标题：Impact of a Healthy Dietary Pattern on Gut Microbiota and Systemic Inflammation in Humans
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作者：Marie Fanelli Kuczmarski ; Rhonda S. Sebastian ; Joseph D. Goldman 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2018
卷号：10
期号：11
页码：1783-1798
DOI：10.3390/nu10111783
出版社：MDPI Publishing
摘要：Gut microbiota have recently been suggested to play a part in low-grade systemic inflammation, which is considered a key risk factor for cardiometabolic disorders. Diet is known to affect gut microbiota; however, the effects of diet and dietary components on gut microbiota and inflammation are not fully understood. In the present review, we summarize recent research on human dietary intervention studies, investigating the effects of healthy diets or dietary components on gut microbiota and systemic inflammation. We included 18 studies that reported how different dietary components altered gut microbiota composition, short-chain fatty acid levels, and/or inflammatory markers. However, the heterogeneity among the intervention studies makes it difficult to conclude whether diets or dietary components affect gut microbiota homeostasis and inflammation. More appropriately designed studies are needed to better understand the effects of diet on the gut microbiota, systemic inflammation, and risk of cardiometabolic disorders.
关键词：gut microbiota; inflammation; diet; humans; intervention studies gut microbiota ; inflammation ; diet ; humans ; intervention studies