文章基本信息

标题：Home Parenteral Nutrition in Patients with Intestinal Failure: Possible Undetected Complications
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作者：Lidia Santarpia ; Giulio Viceconte ; Maria Foggia 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2019
卷号：11
期号：3
页码：581-588
DOI：10.3390/nu11030581
出版社：MDPI Publishing
摘要：Background: Septic pulmonary embolism (SPE) may be a frequently undetected complication of central venous catheter (CVC)-related bloodstream infections (CRBSIs). Materials and Methods: The incidence of SPE was evaluated in a cohort of non-oncological patients on home parenteral nutrition (HPN) who were hospitalized for a CRBSI from January 2013 to December 2017. The main clinical, microbiological, and radiological features and the therapeutic approach were also described. Results: Twenty-three infections over 51,563 days of HPN therapy were observed, corresponding to an infection rate of 0.45/1000. In 10 out of the 23 cases (43.5%), pulmonary lesions compatible with SPE were identified. Conclusion: Our results demonstrated that a CRBSI can produce asymptomatic SPE with lung infiltrates in 43.5% of the cases, suggesting the need to check for secondary lung infections to choose the most appropriate antimicrobial therapy.
关键词：central venous catheter related bloodstream infection; home parenteral nutrition; septic pulmonary embolism; parenteral nutrition central venous catheter related bloodstream infection ; home parenteral nutrition ; septic pulmonary embolism ; parenteral nutrition