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标题：Dietary Acid Load and Cardiometabolic Risk Factors—A Narrative Review
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作者：Joanna Ostrowska ; Justyna Janiszewska ; Dorota Szostak-Węgierek 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：11
页码：3419-3438
DOI：10.3390/nu12113419
出版社：MDPI Publishing
摘要：The Western, diet rich in acidogenic foods (e.g., meat, fish and cheese) and low in alkaline foods (e.g., vegetables, fruits and legumes), is deemed to be a cause of endogenous acid production and elevated dietary acid load (DAL), which is a potential cause of metabolic acidosis. Multiple authors have suggested that such a dietary pattern increases the excretion of calcium and magnesium, as well as cortisol secretion. In addition, it is associated with decreased citrate excretion. All of these seem to increase blood pressure and insulin resistance and may contribute to the development of cardiometabolic disorders. However, there are inconsistencies in the results of the studies conducted. Therefore, this narrative literature review aims to present the outcomes of studies performed in recent years that investigated the association between DAL and the following cardiometabolic risk factors: blood pressure, hypertension, carbohydrate metabolism and lipid profile. Study outcomes are divided into (i) statistically significant positive association, (ii) statistically significant inverse association, and (iii) no statistically significant association.
关键词：dietary acid load; hypertension; insulin resistance; type 2 diabetes mellitus; lipid profile dietary acid load ; hypertension ; insulin resistance ; type 2 diabetes mellitus ; lipid profile