文章基本信息

标题：Vitamin D and Sarcopenia: Potential of Vitamin D Supplementation in Sarcopenia Prevention and Treatment
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作者：Ran Uchitomi ; Mamoru Oyabu ; Yasutomi Kamei 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：10
页码：3189-3200
DOI：10.3390/nu12103189
出版社：MDPI Publishing
摘要：Skeletal muscle, the largest organ in the human body, accounting for approximately 40% of body weight, plays important roles in exercise and energy expenditure. In the elderly, there is often a progressive decline in skeletal muscle mass and function, a condition known as sarcopenia, which can lead to bedridden conditions, wheelchair confinement as well as reducing the quality of life (QOL). In developed countries with aging populations, the prevention and management of sarcopenia are important for the improvement of health and life expectancy in these populations. Recently, vitamin D, a fat-soluble vitamin, has been attracting attention due to its importance in sarcopenia. This review will focus on the effects of vitamin D deficiency and supplementation on sarcopenia.
关键词：vitamin D; sarcopenia; atrophy; skeletal muscle; gene regulation; nuclear receptor vitamin D ; sarcopenia ; atrophy ; skeletal muscle ; gene regulation ; nuclear receptor