文章基本信息

标题：Oxidative Stress in Chronic Liver Disease and Portal Hypertension: Potential of DHA as Nutraceutical
本地全文：下载
作者：Zoe Boyer-Diaz ; Paloma Morata ; Peio Aristu-Zabalza 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：9
页码：2627-2639
DOI：10.3390/nu12092627
出版社：MDPI Publishing
摘要：Chronic liver disease constitutes a growing public health issue worldwide, with no safe and effective enough treatment clinical scenarios. The present review provides an overview of the current knowledge regarding advanced chronic liver disease (ACLD), focusing on the major contributors of its pathophysiology: inflammation, oxidative stress, fibrosis and portal hypertension. We present the benefits of supplementation with docosahexaenoic acid triglycerides (TG-DHA) in other health areas as demonstrated experimentally, and explore its potential as a novel nutraceutical approach for the treatment of ACLD and portal hypertension based on published pre-clinical data.
关键词：TG-DHA; omega-3; oxidative stress; cirrhosis; liver fibrosis; inflammation TG-DHA ; omega-3 ; oxidative stress ; cirrhosis ; liver fibrosis ; inflammation