文章基本信息

标题：Randomized Single-Case Experimental Designs in Healthcare Research: What, Why, and How?
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作者：René Tanious ; Patrick Onghena
期刊名称：Healthcare
电子版ISSN：2227-9032
出版年度：2019
卷号：7
期号：4
页码：143-161
DOI：10.3390/healthcare7040143
出版社：MDPI Publishing
摘要：Health problems are often idiosyncratic in nature and therefore require individualized diagnosis and treatment. In this paper, we show how single-case experimental designs (SCEDs) can meet the requirement to find and evaluate individually tailored treatments. We give a basic introduction to the methodology of SCEDs and provide an overview of the available design options. For each design, we show how an element of randomization can be incorporated to increase the internal and statistical conclusion validity and how the obtained data can be analyzed using visual tools, effect size measures, and randomization inference. We illustrate each design and data analysis technique using applied data sets from the healthcare literature.
关键词：single-case experimental designs; visual analysis; effect sizes; randomization tests single-case experimental designs ; visual analysis ; effect sizes ; randomization tests