文章基本信息

标题：Phytopharmacological Strategies in the Management of Type 2 Diabetes Mellitus
本地全文：下载
作者：Ana M. Duarte ; Maria P. Guarino ; Sónia Barroso 等
期刊名称：Foods
电子版ISSN：2304-8158
出版年度：2020
卷号：9
期号：3
页码：271-301
DOI：10.3390/foods9030271
出版社：MDPI Publishing
摘要：Type 2 Diabetes Mellitus (T2DM) is a chronic disease which corresponds to 90% of the worldwide cases of diabetes, mainly due to epigenetic factors such as unhealthy lifestyles. First line therapeutic approaches are based on lifestyle changes, most of the time complemented with medication mostly associated with several side effects and high costs. As a result, the scientific community is constantly working for the discovery and development of natural therapeutic strategies that provide lower financial impact and minimize side effects. This review focus on these nature-based therapeutic strategies for prevention and control of T2DM, with a special emphasis on natural compounds that present pharmacological activity as dipeptidyl peptidase-4 (DPP4), alpha-amylase, alpha-glucosidase, lipase, and protein tyrosine phosphatase 1B (PTP1B) inhibitors.
关键词：type 2 diabetes mellitus; phytopharmacology; dipeptidyl peptidase-4 (DPP4); alpha-amylase; alpha-glucosidase; lipase; protein tyrosine phosphatase 1B (PTP1B) type 2 diabetes mellitus ; phytopharmacology ; dipeptidyl peptidase-4 (DPP4) ; alpha-amylase ; alpha-glucosidase ; lipase ; protein tyrosine phosphatase 1B (PTP1B)