文章基本信息

标题：Preparation and Characterization of Perforated SERS Active Array for Particle Trapping and Sensitive Molecular Analysis
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作者：István Rigó ; Miklós Veres ; Tamás Váczi 等
期刊名称：Biosensors
电子版ISSN：2079-6374
出版年度：2019
卷号：9
期号：3
页码：93-101
DOI：10.3390/bios9030093
出版社：MDPI Publishing
摘要：A gold-coated array of flow-through inverse pyramids applicable as substrate for entrapment and immobilization of micro-objects and for surface enhanced Raman spectroscopic measurements was fabricated using bulk micromachining techniques from silicon. Surface morphology, optical reflectance, immobilization properties, and surface enhanced Raman amplification of the array were modelled and characterized. It was found that the special perforated periodic 3D structure can be used for parallel particle and cell trapping and highly sensitive molecular analysis of the immobilized objects.
关键词：surface enhanced Raman spectroscopy; SERS array; bulk micromachining; particle/cell entrapment; FDTD surface enhanced Raman spectroscopy ; SERS array ; bulk micromachining ; particle/cell entrapment ; FDTD