文章基本信息

标题：The Role of Electronic Noses in Phenotyping Patients with Chronic Obstructive Pulmonary Disease
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作者：Simone Scarlata ; Panaiotis Finamore ; Martina Meszaros 等
期刊名称：Biosensors
电子版ISSN：2079-6374
出版年度：2020
卷号：10
期号：11
页码：171-190
DOI：10.3390/bios10110171
出版社：MDPI Publishing
摘要：Chronic obstructive pulmonary disease (COPD) is a common progressive disorder of the respiratory system which is currently the third leading cause of death worldwide. Exhaled breath analysis is a non-invasive method to study lung diseases, and electronic noses have been extensively used in breath research. Studies with electronic noses have proved that the pattern of exhaled volatile organic compounds is different in COPD. More recent investigations have reported that electronic noses could potentially distinguish different endotypes (i.e., neutrophilic vs. eosinophilic) and are able to detect microorganisms in the airways responsible for exacerbations. This article will review the published literature on electronic noses and COPD and help in identifying methodological, physiological, and disease-related factors which could affect the results.
关键词：COPD; chronic obstructive pulmonary disease; e-nose; electronic nose; VOCs; volatile organic compounds COPD ; chronic obstructive pulmonary disease ; e-nose ; electronic nose ; VOCs ; volatile organic compounds