文章基本信息

标题：Specific immunological areactivity formation during gestation period in pregnant sows
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作者：Alexander Agarkov ; Anatoly Dmitriev ; Andrey Kvochko 等
期刊名称：E3S Web of Conferences
印刷版ISSN：2267-1242
电子版ISSN：2267-1242
出版年度：2020
卷号：210
页码：1-5
DOI：10.1051/e3sconf/202021006002
出版社：EDP Sciences
摘要：Changes in immunological reactivity to viral and bacterial antigens may cause increased susceptibility to infectious diseases. Different levels of this condition in newborn and adult animal organisms should be based on the fact that the fetus and newborn after birth first comes into contact with the antigen, while the adult body already has partial sensitization. Chronic carrier of pathogens in animals and their influence on the spread of the infectious process is an urgent problem of modern veterinary medicine. The possibility of vaccination in newborns is limited by the presence of maternal antibodies that have an immunosuppressive effect. A high level of functional reserves of the pregnant body is important in the prevention of intrauterine infection. On the one hand, infection in the prenatal period of development affects the processes of growth and development of the fetus, on the other hand, during this period, the mother's body is isoimmunized by fetal antigens, accompanied by increased sensitivity of the body with the predominant manifestation of cellular phenomena in the absence of enhanced antibody synthesis.