文章基本信息

标题：Genetic basis of the probiotic properties of Lactobacillus
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作者：Nikita Korostylev ; Evgenia Prazdnova ; Maria Mazanko 等
期刊名称：E3S Web of Conferences
印刷版ISSN：2267-1242
电子版ISSN：2267-1242
出版年度：2020
卷号：203
页码：4016-4034
DOI：10.1051/e3sconf/202020304016
出版社：EDP Sciences
摘要：The aim of the study is to search and systematize genes associated with the probiotic properties of strains of the genus Lactobacillus, which are symbionts of the gastrointestinal tract of animals. The following purpose were pursued in the study: to establish the molecular features of the probiotic properties of strains of the genus Lactobacillus; to find the genes associated with probiotic properties of Lactobacillus strains; to systematize the genes found according to the molecular characteristics of their products; to characterize these genes, evaluate perspectives of searching for new and using already found ones. Various genomic and proteomic databases were used to search for information on the genetics of probiotic strains. In the course of the study, genes that provide probiotic activity were found, characterized and systematized. These genes are associated with the ability of probiotics to develop in the digestive tract of animals, the ability to attach to the intestinal walls, nutritional characteristics and antipathogenic activity, which manifests in the synthesis of low and high molecular weight metabolites.