摘要: Background The initial years of life particularly the first two years are regarded as the most important brain development period . The development of children is an important determinant of health throughout the whole of life. We aimed to evaluate an educational program to improve the fine motor skills of 18-month-old children. Materials and Methods: This randomized clinical trial was conducted in the city of Saqqez, Iran in 2015-2016. Seventy 18-month-old infants were randomly assigned to control (n=35), and intervention (n=35) groups. The training of fine motor skills was given to the mothers of the children of intervention group, including: painting, building a tower, stringing, tearing and crushing a piece of paper, targeting and dropping. Fine motor skills were measured before intervention and 4 and 8 weeks after the intervention using ASQ-II screening tool (Age and Stage Questionnaire, Second Edition). Data were analyzed using SPSS software version 20.0. Results: In the intervention and control group, 51.5% (n=17) were male and 48.5% (n=16) were female. Statistical test of Chi-square showed that there was no statistically significant difference in terms of gender (p=0.59). According to independent t-test, there was no significant difference in the mean of fine motor score before intervention in the two groups with (p = 0.13). The repeated measurement test showed that 4 and 8 weeks after training, the scores of fine movements with (p = 0.04) became significant. Conclusion Based on the results, developmental skills training compared with control group improved the fine motor skills of 18-month-old children in this study.