文章基本信息

标题：Incidental benefits after fecal microbiota transplant for ulcerative colitis
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作者：Ramit Mahajan ; Vandana Midha ; Arshdeep Singh 等
期刊名称：Intestinal Research
印刷版ISSN：1598-9100
电子版ISSN：2288-1956
出版年度：2020
卷号：18
期号：3
页码：337-340
DOI：10.5217/ir.2019.00108
出版社：Korean Association for the Study of Intestinal Diseases
摘要：Gut dysbiosis can result in several diseases, including infections ( Clostridium difficile infection and infectious gastroenteritis), autoimmune diseases (inflammatory bowel disease, diabetes, and allergic disorders), behavioral disorders and other conditions like metabolic syndrome and functional gastrointestinal disorders. Amongst various therapies targeting gut microbiome, fecal microbiota transplantation (FMT) is becoming a focus in the public media and peer reviewed literature. We have been using FMT for induction of remission in patients with moderate to severe active ulcerative colitis (UC) and also for subsequent maintenance of remission. Four cases reported incidental benefits while being treated with FMT for UC. These included weight loss (n=1), improvement in hair loss (n=1), amelioration of axial arthritis (n=1) and improvement in allergic rhinitis (n=1), thereby suggesting potential clinical applications of FMT in treating extraintestinal diseases associated with gut dysbiosis.
关键词：Fecal microbiota transplantation; Colitis; ulcerative; Incidental findings