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标题：Effect of a medicinal plant (Passiflora incarnata L) on sleep
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作者：Fructuoso Ayala Guerrero ; Graciela Mexicano Medina
期刊名称：Sleep Science
印刷版ISSN：1984-0659
电子版ISSN：1984-0063
出版年度：2017
卷号：10
期号：3
页码：96-100
DOI：10.5935/1984-0063.20170018
出版社：Brazilian Association of Sleep and Latin American Federation of Sleep Societies
摘要：Extracts of the plantPassiflora incarnataL. (Passifloraceae) were administered intraperitoneally in order to test its effects on sleep. Experiments were carried out on chronically implanted male adult wistar rats to obtain cerebral (EEG), ocular (EOG) and muscular (EMG) activities throughout their states of vigilance. Polygraphic recordings were taken during 9 continuous hours before and after the extract administration (500 mg/kg). Passiflora incarnata induced a significant increment in the total sleep time (p<0.05). This increment was due to an increase in the time spent by animals in slow wave sleep (SWS). Concomitantly, a significant decrement in wakefulness (W) was observed (p<0.05). In contrast, time spent in rapid eye movement (REM) sleep showed a decreasing tendency, since both its frequency and mean duration were reduced. The extracts obtained fromPassiflora incarnatacan be considered as appropriated sleep inducers.
关键词：Insomnia;Passifloraceae;Sleep;Sleep Aids; Pharmaceutical;Sleep; REM