文章基本信息

标题：Narcolepsy in pediatric age – Experience of a tertiary pediatric hospital
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作者：Filipa Dias Costa ; Maria Inês Barreto ; Vanda Clemente 等
期刊名称：Sleep Science
印刷版ISSN：1984-0659
电子版ISSN：1984-0063
出版年度：2014
卷号：7
期号：1
页码：53-58
DOI：10.1016/j.slsci.2014.07.022
出版社：Brazilian Association of Sleep and Latin American Federation of Sleep Societies
摘要：Narcolepsy, a chronic disorder of the sleep-wake cycle of multifactorial etiology, is characterized by excessive daytime sleepiness, often associated with cataplexy, hypnagogic/hypnopompic hallucinations and sleep paralysis. Both early clinical suspicion and therapeutic approach are essential for promotion of cognitive development and social integration of these children. The authors present a descriptive retrospective study of a series of eight children in whom symptoms first started between 6.8 and 10.5 years of age. Diagnostic delay ranged from 4 months to 2 years. One child had H1N1 flu vaccination eight months before the clinical onset. The first multiple sleep latency test was positive in 6 of 8 cases. All cases were treated with methylphenidate, and venlafaxine was associated in 4 of them. In one case the initial therapy was exclusively behavioral. In all cases, symptomatic improvement, better school performance and social integration were achieved after therapeutic adjustment.
关键词：Casuistic;Children;Narcolepsy;Sleepiness