文章基本信息

标题：Improvement of Accuracy of Chromosome Aberration Analysis for Biological Radiation Dosimetry
其他标题：Improvement of Accuracy of Chromosome Aberration Analysis for Biological Radiation Dosimetry
本地全文：下载
作者：REIKO KANDA
期刊名称：Journal of Radiation Research
印刷版ISSN：0449-3060
电子版ISSN：1349-9157
出版年度：2000
卷号：41
期号：1
页码：1-8
DOI：10.1269/jrr.41.1
摘要：The frequency of chromosome aberrations in circulating lymphocytes is accepted as being the most reliable indicator of the absorbed dose of radiation. Researches done to improve the accuracy of cytogenetic analysis are described in this review. These include investigations of in vitro factors that affect the yield of radiation-induced aberrations and of in vivo factors that affect the chromosomal radiosensitivity of individuals. Improved chromosome-painting methods for accurate judgment of dicentrics and translocations are introduced. The practicality of these advanced cytogenetic techniques is shown by examinations of individuals exposed in the radiation accident at Tokaimura in 1999.
关键词：Chromosome aberrations; Dose estimation; Human lymphocytes; Improved analysis; Radiation exposures