文章基本信息

标题：X-Ray Sensitivity of Fibroblast Cell Strains Derived from Atomic Bomb Survivors with and without Breast Cancer
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作者：SADAYUKI BAN ; RICHARD B. SETLOW ; HARUO EZAKI 等
期刊名称：Journal of Radiation Research
印刷版ISSN：0449-3060
电子版ISSN：1349-9157
出版年度：1991
卷号：32
期号：SUPPLEMENT
页码：330-338
DOI：10.1269/jrr.32.SUPPLEMENT_330
摘要：Fibroblasts were established in vitro from skin biopsies obtained from 55 women and 1 man with or without breast cancer and with or without exposure to radiations from the atomic bomb (A-bomb) explosion in Hiroshima. The radiosensitivity of these cells was evaluated by clonogenic assays after exposure to X rays. Dose-response curves were fitted to a multitarget model, S/S 0 = A[1-(l-e -D/D 0 ) N ]. There was no difference in the means or variances of radiosensitivity between exposed and nonexposed groups, or between groups with and without breast cancer.
关键词：A-bomb survivors; Breast cancer; Skin fibroblasts; Clonogenic assay; Sensitivity