文章基本信息

标题：Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles
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作者：Koji Inaba ; Satoshi Nakamura ; Hiroyuki Okamoto 等
期刊名称：Journal of Radiation Research
印刷版ISSN：0449-3060
电子版ISSN：1349-9157
出版年度：2016
卷号：57
期号：2
页码：169-173
DOI：10.1093/jrr/rrv055
摘要：Dropped head syndrome (DHS) is a famous but unusual late complication of multimodality treatment for head and neck carcinoma. We reported this early-onset complication and analyzed the dose to the neck extensor muscles. We examined the records of three patients with DHS after radiotherapy. The doses to the neck extensor muscles were compared between three patients with DHS and nine patients without DHS. The mean dose to the neck extensor muscles of the three patients with DHS were 58.5 Gy, 42.3 Gy and 60.9 Gy, while the dose was <50 Gy in all nine patients in the control group. The onset of this syndrome was 5 months, 6 months and 15 months. The early-onset DHS may have something to do with dose to the neck extensor muscles. The proposed dose to the neck extensor muscles might be <46 Gy (or at least <50 Gy).
关键词：chemoradiotherapy;dose constraints to the neck extensor muscles;early-onset dropped head syndrome;radiotherapy;unusual complication