文章基本信息

标题：Does ionizing radiation influence Alzheimer's disease risk?
本地全文：下载
作者：Nasrin Begum ; Bing Wang ; Masahiko Mori 等
期刊名称：Journal of Radiation Research
印刷版ISSN：0449-3060
电子版ISSN：1349-9157
出版年度：2012
卷号：53
期号：6
页码：815-822
DOI：10.1093/jrr/rrs036
摘要：Alzheimer's disease (AD) is a human neurodegenerative disease, and its global prevalence is predicted to increase dramatically in the following decades. There is mounting evidence describing the effects of ionizing radiation (IR) on the brain, suggesting that exposure to IR might ultimately favor the development of AD. Therefore better understanding the possible connections between exposure to IR and AD pathogenesis is of utmost importance. In this review, recent developments in the research on the biological and cognitive effects of IR in the brain will be explored. Because AD is largely an age-related pathology, the effects of IR on ageing will be investigated.
关键词：Alzheimer’s disease; aging; dementia; cognitive effects; ionizing radiation