文章基本信息

标题：Komposisi Asam Lemak Minyak Kelapa Murni (Virgin Coconut Oil) yang Berpotensi sebagai Anti Kandidiasis
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作者：Arina Novilla ; Perdina Nursidika ; Wikan Mahargyani 等
期刊名称：EduChemia
印刷版ISSN：2502-4779
电子版ISSN：2502-4787
出版年度：2017
卷号：2
期号：2
页码：161-173
DOI：10.30870/educhemia.v2i2.1447
出版社：Universitas Sultan Ageng Tirtayasa
摘要：Candida albicans is fungi that cause 50-90% candidiasis in human. Candida albicans is commensal and opportunistic pathogen which interfere gastrointestinal, oropharynx, and female genitalia. Candida albicans resistant to standard antifungal due to repeated use of antifungal. Virgin coconut oil (VCO) contain fatty acid which effective as antifungal. The previous study showed the result of Kirby Bauer method on antifungal effect of 7.5% fatty acid in VCO were able to inhibit Candida albicans, this concentration is equal to nystatin 195 unit. Gas chromatography mass spectrometry showed the fatty acids are caproic acid (0.187%), cyclopropanepentanoic acid (1,12%), nonanoic acid (0.54%), lauric acid (32.73%), myristic acid (28.55%), palmitic acid (17.16%), oleic acid (14.09%), adna octadecanoic acid (5.68%). Saturated and unsaturated fatty acid in VCO are able to inhibit the growth of Candida albicans.
关键词：Antifungal; Candida albicans; candidiasis; fatty acid; VCO