The family Antennariidae is represented by two genera (Antennarius and Histrio) and seven species in the Western Atlantic, and by two genera (Antennarius and Antennatus) and five species in the Eastern Pacific. All the species are known from Colombian waters, with the exception of Antenanrius coccineus. In this study we review the family Antenariidae in Colombia, based on the examination of 51 specimens. Antennarius radiosus is first recorded from the Colombian Caribbean, based on two specimens collected with trawls at 20 m depth in Buritaca (Magdalena) and Isla Fuerte (Córdoba). Antennarius radiosus, Antennarius bermudensis, Antennarius multiocellatus, Antennarius ocellatus and Antennarius pauciradiatus are restricted to the Western Atlantic. The most common species found in Colombian seas are Antennarius striatus in the Caribbean and Antennarius avalonis in the Pacific. Histrio histrio is the only species with an almost circumglobal distribution. A key to identify antenariid fishes from Colombia is provided.