摘要:The need to deepen theoretical research on the reproduction of regional natural-economic systems, the mechanism of their economic transformation and the development of methodological foundations for further improving the development of the region is one of the basic issues in the implementation of the strategy for sustainable development, determining the most effective directions for solving environmental management and environmental protection problems. The processes of transformation of natural-economic systems of a regional level are caused, first, by factors that contribute to the transfer of part of the reserves of natural resources into the natural-resource potential of the regions. Thus, the development of scientific and technological progress contributes to the reduction of current and investment costs for the extraction and processing of natural resources in the context of new technical capabilities. The role of the latter is also high in solving the problem of exceeding the growth rate of the use of natural resources in comparison with their reproduction and restoration. The rationalization of the use of reserves of natural resources, which is justified by the ever-increasing needs of society, necessitates the economic assessment of different gradation of natural resources in terms of quantitative and qualitative analysis. In this regard, the article attempts to find an answer to a number of questions about the content, object, mechanism of development of the natural-economic system based on the natural resource potential of the region.