摘要:Brachytherapy concerns primarily the use of radioactive sealed sources which are inserted into catheters or applicators and placed directly into tissue either inside or very close to the target volume.The use of radiation in treatment of patients involves both benefits and risks.It has been reported that early radiation workers had developed radiation induced cancers.These incidents lead to continuous work for the improvement of radiation safety of patients and personnel.The use of remote afterloading equipment has been developed to improve radiation safety in the delivery of treatment in brachytherapy.The widespread adoption of high dose rate brachytherapy needs appropriate quality assurance measures to minimize the risks to both patients and medical staff.The radiation safety program covers.five major aspects: quality control,quality assurance,radiation monitoring,preventive maintenance,administrative measures and quality audit This paper will discuss the radiation safety program developed for a high dose rate brachytherapy facility at our centre which may serve as a guideline for other centres intending to install a similar facility.