文章基本信息

标题：Precision medicine: From concept to clinical practice – A promising challenge!!
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作者：Sougat Ray ; Sunil Goyal
期刊名称：Journal of Marine Medical Society
印刷版ISSN：0975-3605
电子版ISSN：2589-1235
出版年度：2020
卷号：22
期号：1
页码：1-4
DOI：10.4103/jmms.jmms_13_20
语种：English
出版社：Medknow Publications
摘要：In 2011,the US National Research Council initiated a holistic concept of precision medicine (PM),based on the assumption that an individual's variations in genomic and epigenomic determinants will enable personalization of appropriate prevention and treatment interventions.[1] This in contrast to the “one size fits all” strategy for the management of diseases which has got a laid down standard of care.[2] The concept supposedly can predict which treatment to initiate and at what point of time in the natural course of a disease focused on an individual [Figure 1].[3],[4] It has been gaining ground in the last decade,and its application is being discussed. Currently,the National Institute of Health (NIH) has initiated a project on PM where they plan to recruit a cohort of one million volunteer who will provide genetic data,biological samples,and other health information to generate a big data for precise and targeted diagnosis and treatment options for a variety of diseases.