文章基本信息

标题：Effect of Vitamin A to reduce Parasitemia of Switzerland Strain Mice were infected by Plasmodium berghei
其他标题：Pengaruh Pemberian Vitamin A terhadap Penurunan Parasitemia Mencit Strain Swiss yang diinfeksi Plasmodium berghei
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作者：Umi Isnaeni, Retno Sri Iswari ; Umi Isnaeni, Retno Sri Iswari ; Nugrahaningsih WH 等
期刊名称：Biosaintifika: Journal of Biology & Biology Education
印刷版ISSN：2085-191X
电子版ISSN：2338-7610
出版年度：2012
卷号：4
期号：2
页码：121-126
DOI：10.15294/biosaintifika.v4i2.3930
语种：English
出版社：Universitas Negeri Semarang
摘要：Vitamin A is a vitamin that acts as an immunostimulant. This research aims to determine whether the administration of vitamin A can reduce parasitaemia of Plasmodium berghei in Switzerland strain mice. This research used 24 mice Switzerland strain mice 6-8 weeks old weighing 20-30 grams/tail. Research conducted experimentally by using time series design. In this research, the provision of vitamin A treatment with 3 doses of variation is 0 IU/g BW, 35 IU/g BW and 70 IU/g BW as well as the negative control group, with each group consisting of 6 mice. Vitamin A was given 1 hour before infection then treated mice to mice in the negative control group died. Thin blood smears were made 2 days and parasitaemia was calculated by Giemsa staining. Parasitaemia data were analyzed with ANOVA. Significant results then followed by a further test Post hoc at 1% error level. ANOVA test results for the treatment group B, C and D obtained value of p <0.001 for each treatment group. It is claimed that there are significant differences in the treatment given. Likewise for further Post hoc testing that has been done obtained value of p <0.001. It can be concluded that the administration of vitamin A affects the reduction in parasitaemia of Plasmodium berghei in Switzerland strain mice.
其他摘要：Vitamin A merupakan vitamin yang berperan sebagai imunostimulan. Penelitian ini bertujuan untuk mengetahui apakah pemberian vitamin A dapat menurunkan parasitemia Plasmodium berghei pada mencit strain Swiss. Penelitian ini menggunakan 24 ekor mencit strai
关键词：parasitemia; Plasmodium berghei; switzerland strain mice; vitamin A