文章基本信息

标题：CHARACTERIZATION AND TOXICITY TEST OF PUFFER FISH FROM PAMEUNGPEUK WATERS, WEST JAVA
其他标题：KARAKTERISASI DAN UJI TOKSISITAS IKAN BUNTAL DARI PERAIRAN PAMEUNGPEUK, JAWA BARAT
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作者：Eka Deskawati ; Eka Deskawati ; Sri Purwaningsih 等
期刊名称：E-Journal Ilmu dan Teknologi Kelautan Tropis
印刷版ISSN：2087-9423
电子版ISSN：2085-6695
出版年度：2014
卷号：6
期号：1
页码：101-107
DOI：10.29244/jitkt.v6i1.8631
语种：English
出版社：Bogor Agricultural University
摘要：A puffer fish contains a secondary metabolite toxic called tetrodotoxin (TTX), which can be used as an anesthetic and medication to relieve chronic pain for cancer patients. The purposes of this study were to determine the LC50 value and chemical composition of extracts from various tissues of puffer fishes as a first step to determine the further isolation of tetrodotoxin. In this study various tissues from meat, liver, skin, heart, and ovary of Arothron hispidus and Diodon hystrix species were extracted, characterized, and tested levels of toxicity using Brine Shrimp Lethality Test (BSLT) methods. Between the two puffer fishes studied, the highest toxicity was found in Arothron hispidus ovary with LC50 value of 29.65 ppm. Chemical constituents of the ovary were alkaloids, carbohydrates, and amino acids. Toxic compounds found in the extracts of puffer fish ovaries were tetrodotoxin which is a compound of the alkaloid class of secondary metabolites.
其他摘要：Ikan buntal memiliki metabolit sekunder berupa racun yang bernama tetrodotoxin (TTX) yang dapat dimanfaatkan sebagai obat anastesi dan obat untuk mengurangi rasa sakit kronis yang dialami pasien kanker. Penelitian ini bertujuan untuk menentukan nilai LC50
关键词：Puffer fish; Arothron hispidus; Diodon hystrix; toxicity; Brine Shrimp Lethality Test
其他关键词：Ikan buntal; Arothron hispidus; Diodon hystrix; racun; Brine Shrimp Lethality Test