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标题：Role of Organic Carbon and Nitrogen of Mineral Waters in Their Neuro-Endocrine Effects at Female Rats
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作者：Walery Zukow ; Walery Zukow ; Magdalena Hagner-Derengowska 等
期刊名称：International Journal of Applied Exercise Physiology
电子版ISSN：2322-3537
出版年度：2020
卷号：9
期号：4
页码：20-26
语种：English
出版社：Asian Exercise and Sport Science Association
摘要：Background. Drinking mineral water, along with fresh water, is one of the environmental factors that affect the condition of the human body. Organic substances, despite their presence in all drinking mineral waters, are still considered to be active only in the water of Naftussya type (which, due to mineralization less than 1 g/L, are not formally mineral), whereas the physiological activity of true mineral waters (which mineralization is greater than 1-2 g/L) are associated with electrolytes and trace elements. The purpose of this study was to clarify the role of organic carbon and nitrogen of mineral waters in their effects on certain neuro-endocrine parameters. Material and Methods. Experiment was performed on 48 healthy female Wistar rats 240-290 g divided into 5 groups. Animals of the first group for 6 days administered a single tap water through the probe at a dose of 1,5 mL/100 g of body mass. In the second group we administered the water Naftussya from the Truskavets’ layer, in the third group the water Sophiya of the Truskavets’ field.The rats of the fourth group received the native water from the Gertsa (Bucovyna) field, and the last group its artificial salt analogue. The day after the completion of the drinking course in all rats HRV and endocrine parameters were registered. Results. On the basis of the correlation analysis with step-by-step exclusion, four endocrine parameters are included in the regressive model for organic nitrogen (R=0,543; R2=0,295; Adjusted R2=0,229; F(4,4)=4,5; p=0,004) and three parameters for organic carbon (R=0,407; R2=0,165; Adjusted R2=0,109; F(3,4)=2,9; p=0,045). Together, the organic components of the chemical composition of loading fluids determine their effect on the endocrine parameters by 39%. Conclusion. Organic substances of mineral waters play an essential role in their effects on the endocrine parameters of female rat.
关键词：Mineral waters; organic carbon and nitrogen; female rats; HRV; endocrine parameters