文章基本信息

标题：Comparison of Lactate Threshold, Glucose, and Insulin Levels Between OLETF and LETO Rats After All-Out Exercise
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作者：Hyukki Chang ; Hyukki Chang ; Jae-Young Park 等
期刊名称：Journal of Sports Science and Medicine
印刷版ISSN：1303-2968
出版年度：2009
卷号：8
期号：3
页码：381-387
语种：English
出版社：University of Uludag
摘要：Otsuka Long-Evans Tokushima Fatty (OLETF) rats are an animal model for obesity and Non Insulin Dependent Diabetes Mellitus by hyperphagia. The lactate threshold (LT) is used to determinate aerobic capacity and exercise intensity in individuals. The purpose of this study was to determine whether velocity at the LT (VLT), glucose, and insulin levels of OLETF differs from Long-Evans Tokushima (LETO) rats after all-out exercise on treadmill running. In the results, we found that VLT level of OLETF rats (17.8 ± 1.39 m·min-1) was significantly lower than that of the LETO rats (20.5 ± 1.33 m·min-1). The blood glucose levels immediately after all-out exercise increased in OLETF (from 7.23 ± 0.36 to 9.38 ± 1.77 mmol·L-1) and decreased in LETO rats (from 6.36 ± 0.27 to 4.42 ± 0.71 mmol·L-1), and the insulin level was decreased in both the OLETF (from 34.4 ± 7.7 to 20.13 ± 8.63 µU·mL-1) and LETO (from 15.29 ± 2.6 to 5.72 ± 1.49 µU·mL-1) rats immediately after the all-out exercise, but the difference was not significant. Our results suggest that the different VLT, blood glucose and insulin levels should be considered to compensate for the differences between the OLETF and LETO rats. Moreover, the VLT will be a useful reference for the future studies on exercise training of OLETF rats.
关键词：NIDDM;OLETF;treadmill running;all-out exercise;lactate;velocity of lactate threshold