文章基本信息

标题：Exercise Performance and Muscle Contractile Properties After Creatine Monohydrate Supplementation in Aerobic-Anaerobic Training Rats
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作者：Nickolay Boyadjiev ; Nickolay Boyadjiev ; Dobrin Popov 等
期刊名称：Journal of Sports Science and Medicine
印刷版ISSN：1303-2968
出版年度：2007
卷号：6
期号：4
页码：423-428
语种：English
出版社：University of Uludag
摘要：The purpose of this study was to investigate the effects of creatine monohydrate supplementation on exercise performance and contractile variables in aerobic-anaerobic training rats. Twenty 90-day-old male Sprague Dawley rats were divided into two groups - creatine (Cr) and controls (K). The creatine group received creatine monohydrate as a nutritional supplement, whereas the control group was given placebo. Both groups were trained 5 days a week on a treadmill for 20 days in a mixed (aerobic-anaerobic) metabolic working regimen (27 m·min-1, 15% elevation for 40 min). The exercise performance (sprint-test), contractile properties (m. tibialis anterior), oxidative enzyme activity (SDH, LDH, NADH2) in m. soleus and blood hematological and chemical variables were assessed in the groups at the end of the experiment. It was found out that creatine supplementation improved the exercise performance after 20 days of administration in a dose of 60 mg per day on the background of a mixed (aerobic-anaerobic) exercise training. At the end of the trial the Cr-group demonstrated better values for the variables which characterize the contractile properties of m. tibialis anterior containing predominantly types IIA and IIB muscle fibers. On the other hand, a higher oxidative capacity was found out in m. soleus (type I muscle fibers) as a result of 20-day creatine supplementation. No side effects of creatine monohydrate supplementation were assessed by the hematological and blood biochemical indices measured in this study.
关键词：Exercise;creatine supplementation;rats;performance;muscle contractile properties