文章基本信息

标题：Profile Protein Autism Analysis Based Bioinformatics as Public Dissemination Materials in Malang about The Potensial Causes Autism
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作者：Rizki Mei Listawati ; Umie Lestari ; Mohammad Amin 等
期刊名称：JPBI (Jurnal Pendidikan Biologi Indonesia)
印刷版ISSN：2442-3750
电子版ISSN：2527-6204
出版年度：2016
卷号：2
期号：3
页码：292-299
DOI：10.22219/jpbi.v2i3.3876
语种：English
出版社：University of Muhammadiyah Malang
摘要：Life currently offers various facilities. However,along with this there are many issues which trigger stress. In addition,there are many chemical elements and heavy metals which,when interacting can cause a variety of illnesses ranging from colds to cancer,including autism. This study aims to analyze the potential of the protein profile in the blood that cause autism based bioinformatics. Then,to inform the public,especially parents of autistic in Malang so as to provide insight into autism. This research could also be developed as the basis of laboratory research. The research is a qualitative descriptive,using three databases,namely the National Center for Biotechnology Information (NCBI),Uniprot,and the Protein Data Bank (PDB) and using software PyMOL. The results of this study show that: 1) protein in the blood that could potentially cause autism based on articles that mTOR,glutathione S transferase P,Chemokines monocyte chemotactic protein-1 (MCP-1),Interferon-∂-Inducible Protein-16 (IFI-16),and serotonin;2) The following proteins were analyzed using three databases (NCBI,Uniprot,and GDP) showed that the protein glutathione S transferase P is more potent against autism. This is because the protein's function is to prevent neurodegeneration;3) Research on the causes of autism is needed by parents of autistic children (society),so as to minimize access to the entry of such triggers..
其他摘要：Kehidupan saat ini menawarkan berbagai kemudahan. Namun,seiring dengan hal tersebut ada banyak permasalahan yang memicu stress. Selain itu,terdapat banyak unsur kimia dan logam berat yang jika saling berinteraksi dapat menimbulkan berbagai macam penyakit
关键词：protein profile;autism;bioinformatics;socialization;community
其他关键词：profil protein;autis;bioinformatik;sosialisasi;masyarakat