文章基本信息

标题：Correction of the ultrastructural changes of the respiratory department of the lungs by phosphatidylcholine liposomes due to multiple skeletal trauma with osteosynthesis in the experimental study
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作者：L.M. Zaiats ; U.V. Kuz ; W. Zukow 等
期刊名称：Journal of Education, Health and Sport
电子版ISSN：2391-8306
出版年度：2018
卷号：8
期号：8
页码：293-301
DOI：10.5281/zenodo.1308228
语种：English
出版社：Kazimierz Wielki University
摘要：It was made the experimental study on white male rats by an electron microscopic method in dynamics (6, 24, 72, 168 h) and was studied the possibility of correction of ultrastructural changes of the respiratory department of the lung by phosphatidylcholine liposomes ("Lipin" medium) due to multiple skeletal trauma with the use of intramedullary osteosynthesis. It is defined that intraperitoneal Lipin administration in dose 50 mg/kg body weight during the first 24 hours after beginning of the study case decrease the expressiveness and prevalence of damage alveolar cells І and ІІ type, haemocapilari endothelial cells and alveolar macrophages. The Lipin administration does not influence on the character of ultrastructural changes of the respiratory department of the lung while increasing time of the experiment (72-168 hours).
关键词：It was made the experimental study on white male rats by an electron microscopic method in dynamics (6, 24, 72, 168 h) and was studied the possibility of correction of ultrastructural changes of the respiratory department of the lung by phosphatidylcholine liposomes ("Lipin" medium) due to multiple skeletal trauma with the use of intramedullary osteosynthesis. It is defined that intraperitoneal Lipin administration in dose 50 mg/kg body weight during the first 24 hours after beginning of the study case decrease the expressiveness and prevalence of damage alveolar cells І and ІІ type, haemocapilari endothelial cells and alveolar macrophages. The Lipin administration does not influence on the character of ultrastructural changes of the respiratory department of the lung while increasing time of the experiment (72-168 hours).