文章基本信息

标题：PARAOXONASE 1 AS AN IMPORTANT ANTIATHEROGENIC AGENT
本地全文：下载
作者：Ewa Krzewicka-Romaniuk ; Dagna Siedlecka ; Anna Warpas 等
期刊名称：Journal of Education, Health and Sport
电子版ISSN：2391-8306
出版年度：2019
卷号：9
期号：1
页码：133-143
DOI：10.5281/zenodo.2542320
语种：English
出版社：Kazimierz Wielki University
摘要：The inverse relationship between High Density Lipoproteins (HDL) level and risk of ischaemic heart disease was proved by many epidemiological studies. Although the main mechanism of antiatherogenic activity of HDL is a reverse transport of cholesterol from peripheral tissues to the liver, HDL additionally carries some antioxidative enzymes like Paraoxonase 1 (PON1) which protects LDL and HDL lipoproteins from oxidative modification. A lot of antiatherogenic activities of HDL depends on PON1 activity.
关键词：The inverse relationship between High Density Lipoproteins (HDL) level and risk of ischaemic heart disease was proved by many epidemiological studies. Although the main mechanism of antiatherogenic activity of HDL is a reverse transport of cholesterol from peripheral tissues to the liver, HDL additionally carries some antioxidative enzymes like Paraoxonase 1 (PON1) which protects LDL and HDL lipoproteins from oxidative modification. A lot of antiatherogenic activities of HDL depends on PON1 activity.