文章基本信息

标题：PATOPHYSIOLOGY OF NONALCOHOLIC FATTY LIVER DISEASE
本地全文：下载
作者：Ewa Krzewicka-Romaniuk ; Dagna Siedlecka ; Marcelina Makuch 等
期刊名称：Journal of Education, Health and Sport
电子版ISSN：2391-8306
出版年度：2019
卷号：9
期号：9
页码：987-991
DOI：10.5281/zenodo.3462889
语种：English
出版社：Kazimierz Wielki University
摘要：Clinically, NAFLD is the most common cause of asymptomatic increases in transaminases. NAFLD is also currently the most common liver disorder in developed countries, affecting 24% of the world's population. The prevalence of NAFLD in European societies is estimated in the range of 17-46% and shows an upward trend with the increasing incidence of obesity and type II diabetes. NAFLD occurs in about 7% of people without excess weight, however, they are usually people with impaired insulin sensitivity, leading a sedentary lifestyle, having an increased cardiovascular risk, with higher levels of hepatic lipids as a result of reduced fat accumulation and reduced mitochondrial activity in adipose tissue and increased de novo hepatic lipogenesis.
关键词：Clinically, NAFLD is the most common cause of asymptomatic increases in transaminases. NAFLD is also currently the most common liver disorder in developed countries, affecting 24% of the world's population. The prevalence of NAFLD in European societies is estimated in the range of 17-46% and shows an upward trend with the increasing incidence of obesity and type II diabetes. NAFLD occurs in about 7% of people without excess weight, however, they are usually people with impaired insulin sensitivity, leading a sedentary lifestyle, having an increased cardiovascular risk, with higher levels of hepatic lipids as a result of reduced fat accumulation and reduced mitochondrial activity in adipose tissue and increased de novo hepatic lipogenesis.