文章基本信息

标题：Major causes of insuline resistance
本地全文：下载
作者：Ewa Krzewicka-Romaniuk ; Dagna Siedlecka ; Anna Pradiuch 等
期刊名称：Journal of Education, Health and Sport
电子版ISSN：2391-8306
出版年度：2019
卷号：9
期号：9
页码：946-952
DOI：10.5281/zenodo.3461607
语种：English
出版社：Kazimierz Wielki University
摘要：The metabolic syndrome is also called insulin resistance syndrome.1 This term was used for the first time in 1922 to describe the few cases of patients with diabetes who required increasing doses of insulin to maintain normoglycemia. Most of these patients developed insulin resistance secondary to the production of antibodies directed against exogenous insulin, which was not sufficiently purified at the time, and what is more, it was obtained from other animal species.2 Insulin resistance is currently defined as the body's insufficient response to specific insulin levels. The clinical spectrum of insulin resistance is broad and includes both diabetic patients who require insulin therapy and experience hyperglycemia despite high doses of exogenous insulin, as well as patients with severe insulin resistance who maintain almost normal blood glucose levels due to significantly higher endogenous insulin secretion.
关键词：The metabolic syndrome is also called insulin resistance syndrome.1 This term was used for the first time in 1922 to describe the few cases of patients with diabetes who required increasing doses of insulin to maintain normoglycemia. Most of these patients developed insulin resistance secondary to the production of antibodies directed against exogenous insulin, which was not sufficiently purified at the time, and what is more, it was obtained from other animal species.2 Insulin resistance is currently defined as the body's insufficient response to specific insulin levels. The clinical spectrum of insulin resistance is broad and includes both diabetic patients who require insulin therapy and experience hyperglycemia despite high doses of exogenous insulin, as well as patients with severe insulin resistance who maintain almost normal blood glucose levels due to significantly higher endogenous insulin secretion.