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标题：CLUSTER ANALYSIS OF HORMONAL CONSTELLATION AT WOMEN AND MEN WITH HARMONIOUS AND DISHARMONIOUS GENERAL ADAPTATION REACTIONS
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作者：Yaroslav L Hrytsak ; Liliya G Barylyak ; Walery Zukow 等
期刊名称：Journal of Education, Health and Sport
电子版ISSN：2391-8306
出版年度：2016
卷号：6
期号：4
页码：141-150
DOI：10.5281/zenodo.49942
语种：English
出版社：Kazimierz Wielki University
摘要：Background. It is known that the nervous, endocrine and immune systems interact closely with each other to form a three-pronged neuro-endocrine-immune complex. On of manifest of causal neuroendocrine-immune relationships is Leukocytogram of peripheral blood that differ by various constellation of Principal Adaptation Hormones. Material and research methods. We determined twice at ten women and ten men aged 33-76 years without clinical diagnose serum levels of Cortisol, Aldosterone, Triiodothyronine, Testosterone and Calcitonin (ELISA) as well as Popovych’s Adaptation Index by Leukocytogram. Results. All case was distributed among four clusters. Cluster N1 contains 5 cases with drastically hypercortisolemia and moderately hypercalcitoninemia; 5 other cases characterized moderately hypercortisolemia and borderline level of Triiodothyronine, together reflected chronic stress. Majority of cases (Cluster N3) characterized upper borderline level of Cortisol and normal levels others hormones, while in 5 cases (Cluster N4) hormonal costellation is also normal but with lower borderline level of Cortisol. Estimation by Leukocytogram Popovych’s Adaptation Index shown that at 25 cases take place Harmonious General Adaptation Reactions (GAR) as markers of health while at 15 cases detected Disharmonious GAR as markers of premorbidic stage. Conclusion. Constellations of principal Adaptation Hormones displays widely variability representing different gradations of health and premobide states. Calcitonin may be considered as one of principal Adaptation Hormones.
关键词：Cortisol;Aldosterone;Triiodothyronine;Testosterone;Calcitonin;General Adaptation Reactions