标题:RELATIONSHIPS BETWEEN POPOVYCH’S ADAPTATION INDEX AND PARAMETERS OF ONGOIGING HRV AND EEG IN PATIENTS WITH CHRONIC PYELONEPHRITE AND CHOLECYSTITE IN REMISSION
摘要:Background. The conception of general adaptation reactions of organism (GARO), created by Garkavi LKh, Kvakina ЕB and Ukolova MA in 1977 on the base of Selye H classic conception of stress and developed then by them (1998), and also by Radchenko ОМ (2004), sufficiently successfully used in medicine and valeology for the estimation of general condition of organism. The downside the concept was qualitative assessment of GIRO. So Popovych IL (2000, 2006) proposed to quantify the various GARO Adaptation Index, which significantly correlated with the levels of key hormones adaptation and HRV parameters as well as phagocytosis. Another disadvantage of the concept is the lack of EEG markers GARO. We set a goal to analyze the relationships Popovych’s Adaptation Index with parameters of HRV and EEG. Methods. In basal conditions in 22 men, patients with chronic pyelonephrite and cholecystite in remission, recorded twice during 9-11 days HRV (“Cardiolab+VSR”, KhAI Medica, Ukraine) and EEG (“NeuroCom Standard”, KhAI Medica, Ukraine). In portion of blood counted up leukocytogram, on the basis of which determined Popovych’s Adaptation Index (PAI). Results. Registered 14 normal (harmonious) GARO, 20 premorbidic (disharmonious) GARO and only 9 reactions of superactivation, in the absence stress-reactions. Revealed the closest relationship between PAI and normalized Power Spectral Density (PSD) LF (r=0,44), Baevskiy’s Stress Index in Orthostase (r=0,41), Laterality Index PSD θ-Rhythm (r=-0,43), PSD β-Rhythm in Right Occipital locus (r=-0,40). Canonical correlation between PAI, on the one hand, and the parameters of HRV and EEG, on the other hand, is strong: R=0,846; R2=0,716; Adjusted R2=0,628; F(10)=8,1; χ2(10)=47,3; p<10-5. Conclusion. Popovych’s Adaptation Index reflects the activity of a number of regulatory nerve structures.
关键词:general adaptation reactions;leukocytogram;index of adaptation by Popovych;HRV;EEG;correlations