标题:NEURO-IMMUNE RELATIONSHIPS AT PATIENTS WITH CHRONIC PYELONEPHRITE AND CHOLECYSTITE. Communication 3. CORRELATIONS BETWEEN PARAMETERS EEG, HRV AND IMMUNOGRAM
摘要:Background. The immunological homunculus conception considers somatotopic organization to СNS regulation of immune system. We set a goal to analyze the causal relationships between parameters of EEG and HRV, on the one hand, and the parameters of immunity, on the other hand. Methods. In basal conditions in 23 men with chronic pyelonephrite and cholecystite in remission, we recorded EEG (“NeuroCom Standard”) and HRV (“Cardiolab+VSR”). In blood estimated routine parameters of Immunity on a set of I and II levels recommended by the WHO. Results. Maximal coefficient canonical correlation (R) parameters of EEG and HRV detected with relative level CD22+ B-Lymphocytes: 0,94 (p<10-4), maximal relationships take place with Spectral Power Density (SPD) absolute (a) Fp1-α (r=-0,64) and relative (r) PSD Fp1-β (r=0,60). R with serum level IgM takes 0,90 (p<10-4), maximal relationships with rSPD O1-θ (r=0,60) and rHF HRV (r=0,52), with serum level IgG takes 0,86 (p<10-3), maximum with rSPD of β-rhythm in loci T6, O1 and O2 (r for all makes 0,40), with serum level IgA takes 0,84 (p<10-4), maximum with Asymmetry of δ-rhythm (r=0,59) and aSPD T4-θ (r=-0,50) as well as with Circulating Immune Complexes: R=0,84 (p<10-4), maximum with Bayevskiy’s Stress Index HRV (r=0,45) and rSPD T3-α (r=0,39). R with relative level CD8+ T-Lymphocytes makes 0,81 (p<10-4), maximal relationships take place with aSPD of α-rhythm in loci P4 (r=-0,38) and P3 (r=-0,31) as well as with rVLF HRV (r=-0,29). R with relative level CD4+ T-Lymphocytes makes 0,79 (p<10-3), maximum with aSPD of β-rhythm in loci F4 (r=0,40) and T3 (r=0,39). R with level CD16+ NK-Lymphocytes makes 0,71 (p=0,009), maximal relationships take place with Index of α-rhythm (r=-0,36) and Entropy SPD in locus C3. Minimal R detected with level “active” T- Lymphocytes: 0,57 (p=0,029). Conclusion. Take place neuro-immune causal relationships in bounds of immunological homunculus conception.