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标题：SURVIVAL OF PATIENTS WITH CHRONIC ISCHEMIC HEART DISEASE DEPENDING ОN THE TYPE OF ADAPTATIONAL REACTION
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作者：Elena Radchenko ; Anzhelika Filipyuk ; Walery Zukow 等
期刊名称：Journal of Education, Health and Sport
电子版ISSN：2391-8306
出版年度：2015
卷号：5
期号：2
页码：125-132
DOI：10.5281/zenodo.15687
语种：English
出版社：Kazimierz Wielki University
摘要：The aim of investigations was to study survival of patients with chronic ischemic heart disease (IHD) depending of the type of adaptational reaction. It was studied correlations between the type of adaptational reactions and the clinical course of chronic IHD in 121 male patients in long-term prospective observation. The diagnosis of IHD was based on clinical examinations, laboratory investigations, electrocardiography, echocardiography, exercise testing, coronary angiography. It was revealed, that distress-reactions (stress, over-activation and defective adaptation) are significant predictors of an unfavorable chronic IHD prognosis. They were associated with acute cardiovascular events onset, functional class III of chronic heart failure, prothrombotic disorders of coagulation haemostasis (high levels of fibrinogen, fibrin-monomer and D-dimer), and dyslipidemia (lower HDL-cholesterol values). Decreasing оf lymphocyte/neutrophil ratio (index of adaptation) is аn informative parameter of distress-reactions and a significant predictor of an unfavorable chronic IHD course.
关键词：adaptational reactions;stress;ischemic heart disease prognosis;fibrin-monomers;lymphocyte/neutrophil ratio