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标题：INFLUENCE BALNEOTHERAPY ON SPA TRUSKAVETS’ WITH TAKING CANEPHRON® N ON URINA LITHOGENICITY AND ITS METABOLIC AND NEUROENDOCRINE-IMMUNE ACCOMPANIMENTS IN PATIENTS WITH CHRONIC PYELONEPHRITE AND CHOLECYSTITE
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作者：Oleksandr V. Shulyak ; Igor-Severyn S. Flyunt ; Victor R. Flyunt 等
期刊名称：Journal of Education, Health and Sport
电子版ISSN：2391-8306
出版年度：2015
卷号：5
期号：11
页码：453-465
DOI：10.5281/zenodo.34351
语种：English
出版社：Kazimierz Wielki University
摘要：Objective. We know that balneotherapy on spa Truskavets' did not significantly affect the parameters of urina Lithogenicity, including Ca/Mg ratio, so search for means of reducing urina Lithogenicity remains relevant. We also know that Phytopreparation Canephron® N recommended for inclusion in complex therapy of chronic pyelonephrite as effective elimination of infectious kidney inflammation, prevention of recurrence of inflammation and lithogenese. Aim: to find out the possibility of reducing urina Lithogenicity influenced balneotherapy on spa Truskavets' by additional taking Canephron® N. Results. Standardized balneotherapy not significantly affect urina Lithogenicity in patients with chronic pyelonephrite and cholecystite, even showed a trend to increase, while additional use Canephron® N significantly reduces urina Lithogenicity by reducing the concentration of Uric acid and downward trend Calcium. Reducing urina Lithogenicity accompanied by a decrease urina concentration Chloride and Potassium, and Baevskiy’s Activity Regulatory Systems Index, Asymmetry δ-, θ- and α-rhythms of background EEG and α-rhythm normalized Power Spectrum Density (PSD) in right loci Fp2, F8, T6 and O2, while HRV markers of vagal tone (RMSSD, pNN50, TI) also Frequency Deviation θ- and β-rhythms, Amplitude β- and δ-rhythms, δ-rhythm PSD in loci Fp2, F8, T3, T5, O1, O2, β-rhythm PSD in loci Fp1, F4 and θ-rhythm PSD in loci T3 and F7 rising. However, Canephron® N preventes or reverses increasing Uric acid plasma level, Mineralocorticoide Activity, Sympathetic tone, Baevskiy’s Stress Index and PSD ULF HRV also decreasing PSD VLF HRV. Concerning parameters of Immunity Canephron® N decreases blood level active T-Lymphocytes but increases level B-Lymphocytes, Stubnucleary Neutrophiles and total Leukocytes also prevents or reverses increasing CD16+ NK-Lymphocytes, CD8+ and Theophilinesensitive T-Lymphocytes, Monocytes and serum IgM also decreasing CD4+ T-Lymphocytes and Neutrophiles Phagocytose Count vs Staphylococcus aureus. In addition, Canephron® N potentiates increasing Parathyrine Activity, serum level IgG and Bactericidic Capacity of Neutrophiles vs Staphylococcus aureus also decreasing Urea and Creatinine plasma level, Sodium urina concentration and Neutrophiles Phagocytose Count vs Escherichia coli. Conclusion. Introduce Canephron® N into standard balneotherapeutic complex spa Truskavets’ contribute to decrease urina Lithogenicity accompanied by decreasing of HRV and EEG markers of chronic Stress and favorable modulation parameters of Immunity in patients with chronic pyelonephrite and cholecystite.
关键词：lithogenicity of urina;EEG;HRV;immunity;spa Truskavets’;Canephron® N