文章基本信息

标题：Development of Hydrophilic Polyacrylamide Gel-Based Condensing Reagents Comprised of Chlorotriazine
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作者：Kohei Yamada ; Shota Hirozawa ; Junqing Xia 等
期刊名称：Chemical and Pharmaceutical Bulletin
印刷版ISSN：0009-2363
电子版ISSN：1347-5223
出版年度：2020
卷号：68
期号：6
页码：534-537
DOI：10.1248/cpb.c20-00074
出版社：The Pharmaceutical Society of Japan
摘要：Hydrophilic polyacrylamide gel-based triazine-type condensing reagents, PAG-Trz-Cl, have been developed. PAG-Trz-Cls were synthesized using a chlorotriazine with an acrylamide moiety, acrylamide, and N , N ′-methylenebisacrylamide via both precipitation and solution polymerization. Because PAG-Trz-Cls adequately swell in aqueous media, the amidation between polar carboxylic acids and amines afforded the corresponding amides in good yields.
关键词：aqueous solvent;condensation;polyacrylamide;triazine