文章基本信息

标题：Global Vitamin C Status and Prevalence of Deficiency: A Cause for Concern?
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作者：Sam Rowe ; Anitra C. Carr
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：7
页码：1-20
DOI：10.3390/nu12072008
出版社：MDPI Publishing
摘要：Vitamin C is an essential nutrient that must be obtained through the diet in adequate amounts to prevent hypovitaminosis C, deficiency and its consequences—including the potentially fatal deficiency disease scurvy. Global vitamin C status and prevalence of deficiency has not previously been reported, despite vitamin C’s pleiotropic roles in both non-communicable and communicable disease. This review highlights the global literature on vitamin C status and the prevalence of hypovitaminosis C and deficiency. Related dietary intake is reported if assessed in the studies. Overall, the review illustrates the shortage of high quality epidemiological studies of vitamin C status in many countries, particularly low- and middle-income countries. The available evidence indicates that vitamin C hypovitaminosis and deficiency is common in low- and middle-income countries and not uncommon in high income settings. Further epidemiological studies are required to confirm these findings, to fully assess the extent of global vitamin C insufficiency, and to understand associations with a range of disease processes. Our findings suggest a need for interventions to prevent deficiency in a range of at risk groups and regions of the world.
关键词：vitamin C status; hypovitaminosis C; vitamin C deficiency; low and middle income; LMIC; dietary intake; supplement; non-communicable disease; communicable disease; infection vitamin C status ; hypovitaminosis C ; vitamin C deficiency ; low and middle income ; LMIC ; dietary intake ; supplement ; non-communicable disease ; communicable disease ; infection