摘要:Background: Affects, both positive and negative, can act as mediators between self-esteem and happiness. The present study is undertaken among 812 university students in order to examine the relationship between these variables. Methods: The sample included 812 university students – 361 men (44.46%) and 451 women (55.54%) – who participated voluntarily. The Positive and Negative Affect Scale, Subjective Happiness Scale and Self-Esteem Scale were the instruments used in this study. Results: The results revealed that men have greater self-esteem and positive affects, while women scored higher in terms of subjective happiness. The analysis revealed a significant correlation between the variables under analysis. Positive affects show a strong positive correlation between self-esteem and happiness, while negative affects show a negative correlation. Mediation analysis suggests that affects, both positive and negative, mediate the relationship between self-esteem and subjective happiness. The results of this study may present us with new perspectives concerning the role that affects play between self-esteem and happiness. Conclusion: The data present evidence of the mediating role-played by affects, both positive and negative, in the relationship between self-esteem and happiness. More research is needed to examine to what extent these results can be extrapolated, and how to design measures to improve psychological health and well-being.