文章基本信息

标题：Onchocerciasis dynamics: modelling the effects of treatment, education and vector control
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作者：Asha Hassan ; Nyimvua Shaban
期刊名称：Journal of Biological Dynamics
印刷版ISSN：1751-3758
电子版ISSN：1751-3766
出版年度：2020
卷号：14
期号：1
页码：245-268
DOI：10.1080/17513758.2020.1745306
出版社：Taylor & Francis
摘要：Abstract Formulae display: ? Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. A deterministic model of onchocerciasis disease dynamics is considered in a community partitioned into compartments based on the disease status. Public health education is offered in the community during the implementation of mass treatment using ivermectin drugs. Also, larviciding and trapping strategies are implemented in the vector population with the aim of controlling population growth of black flies. We fit the model to the data to check the suitability of the model. Expressions are derived for the influence on the reproduction numbers of these strategies. Numerical results show that the dynamics of onchocerciasis and the growth of black flies are best controlled when the four strategies are implemented simultaneously. Also, the results suggest that for the elimination of the disease in the society there is a need for finding another drug which will be implemented to ineligible human as well as killing the adult worms instead of ivermectin.
关键词：Onchocerciasis; ivermectin; public health education; larviciding; trapping