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  • 标题:Can Magnetic Resonance Imaging Predict Pathologic Findings for Endometrioid Endometrial Cancer?
  • 本地全文:下载
  • 作者:Dickson Michelson, Elizabeth L ; Kram, Jessica J. F. ; Heslin, Kayla
  • 期刊名称:Journal of Patient-Centered Research and Reviews
  • 电子版ISSN:2330-0698
  • 出版年度:2020
  • 卷号:7
  • 期号:2
  • 页码:206-212
  • DOI:10.17294/2330-0698.1720
  • 出版社:Aurora Health Care
  • 摘要:This pilot study aimed to assess the feasibility of precisely measuring tumor diameter and myometrial invasion in patients with endometrioid endometrial cancer (EEC) using preoperative contrastenhanced magnetic resonance imaging (MRI). Adult patients with confirmed diagnosis of complex hyperplasia with atypia or EEC were included. Three radiologists separately measured tumor diameter and myometrial invasion. Basic descriptive statistics were used to describe patient characteristics and to compare radiology- and pathology-measured tumor diameter and myometrial invasion. Using the pathology results for tumor diameter as the gold standard for comparison, at least 1 radiologist was able to predict largest tumor diameter within 5 mm for 41.7% of patients. Similarly, based on pathology results for myometrial invasion, at least 1 radiologist was able to predict myometrial invasion within 5% for 50% of patients. All radiologists were able to predict superficial (<50%) or deep (≥50%) myometrial invasion for 75% of patients, with greater sensitivity, specificity, and accuracy for deep myometrial invasion. Given variation among radiologic measurements, it is difficult to recommend preoperative MRI as a basis for measuring tumor diameter and myometrial invasion. Even so, the ability to predict superficial versus deep myometrial invasion may benefit patients with EEC for whom surgery is not a viable option or for those seeking fertility-sparing treatment options.
  • 关键词:magnetic resonance imaging; endometrioid endometrial cancer; tumor diameter; myometrial invasion
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