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标题：POTENCY OMEGA-9 OLEIC ACID IN THE AVOCADO FRUIT MESOCARP CHOLESTEROL LOWERING BLOOD SERUM
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作者：Eny Hartadiyati Wasikin Haryanti
期刊名称：Bioma
印刷版ISSN：2086-5481
电子版ISSN：2549-9890
出版年度：2011
卷号：1
期号：1, April
页码：1-8
DOI：10.26877/bioma.v1i1, April.81
出版社：Universitas PGRI Semarang
摘要：Avocado is high in fat, contained in the development of forms of mono-unsaturated fats (monounsaturated fatty acids), namely omega-9: 72.2% oleic acid. This fatty acid configuration can inhibit the absorption of cholesterol in intestines and not easily oxidized than linoleum and lino-lenic acid. Therefore, it improves blood serum cholesterol levels. This study aims to analyze the changes in HDL and LDL cholesterol in the serum of mice?é?á hypercholesterolemic effect of omega-9 oleic acid on the avocado fruit mesocarp . The design of this study is the pre and post with control group (ran-domized control pre post test design). Animal experiment ( Rattus norve-gicus strain Sprague Dawley) was given treatment: P0 group was given standard food 0 mg avocado fruit mesocarp; P1 groups was given stan-dard food avocado fruit mesocarp dose 1.35 g / day; the group P2 was given standard food avocado fruit mesocarp 2.7 g / day; groups P3 of rats was given standard food avocado fruit mesocarp dose 4.05 g / day. The result showed a decrease of ?é?áblood serum levels of LDL cholesterol, and elevated levels of blood serum HDL cholesterol, which is significant at 5% probability level. The conclusion is oleic acid omega-9 in the avocado fruit mesocarp?é?á has the potential to lower LDL cholesterol blood serum of rats.
其他摘要：Avocado is high in fat, contained in the development of forms of mono-unsaturated fats (monounsaturated fatty acids), namely omega-9: 72.2% oleic acid. This fatty acid configuration can inhibit the absorption of cholesterol in intestines and not easily oxidized than linoleum and lino-lenic acid. Therefore, it improves blood serum cholesterol levels. This study aims to analyze the changes in HDL and LDL cholesterol in the serum of mice?é?á hypercholesterolemic effect of omega-9 oleic acid on the avocado fruit mesocarp . The design of this study is the pre and post with control group (ran-domized control pre post test design). Animal experiment ( Rattus norve-gicus strain Sprague Dawley) was given treatment: P0 group was given standard food + 0 mg avocado fruit mesocarp; P1 groups was given stan-dard food + avocado fruit mesocarp dose 1.35 g / day; the group P2 was given standard food + avocado fruit mesocarp 2.7 g / day; groups P3 of rats was given standard food + avocado fruit mesocarp dose 4.05 g / day. The result showed a decrease of ?é?áblood serum levels of LDL cholesterol, and elevated levels of blood serum HDL cholesterol, which is significant at 5% probability level. The conclusion is oleic acid omega-9 in the avocado fruit mesocarp?é?á has the potential to lower LDL cholesterol blood serum of rats.
关键词：omega-9 oleic acid; cholesterol; avocado; blood serum; LDL; HDL