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标题：Complete genome sequence of thermophilic Bacillus smithii type strain DSM 4216 T
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作者：Elleke F. Bosma ; Jasper J. Koehorst ; Sacha A. F. T. van Hijum 等
期刊名称：Environmental Microbiome
印刷版ISSN：2524-6372
出版年度：2016
卷号：11
期号：1
页码：1-11
DOI：10.1186/s40793-016-0172-8
摘要：Bacillus smithii is a facultatively anaerobic, thermophilic bacterium able to use a variety of sugars that can be derived from lignocellulosic feedstocks. Being genetically accessible, it is a potential new host for biotechnological production of green chemicals from renewable resources. We determined the complete genomic sequence of the B. smithii type strain DSM 4216T, which consists of a 3,368,778 bp chromosome (GenBank accession number CP012024.1) and a 12,514 bp plasmid (GenBank accession number CP012025.1), together encoding 3880 genes. Genome annotation via RAST was complemented by a protein domain analysis. Some unique features of B. smithii central metabolism in comparison to related organisms included the lack of a standard acetate production pathway with no apparent pyruvate formate lyase, phosphotransacetylase, and acetate kinase genes, while acetate was the second fermentation product.
关键词：Bacillus smithii;Genome sequence;Lactic acid;Thermophile;Thermophilic bacillus;Biotechnology