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标题：The roles of microRNA in redox metabolism and exercise-mediated adaptation
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作者：Ferenc Torma ; Zoltan Gombos ; Matyas Jokai 等
期刊名称：Journal of Sport and Health Science
印刷版ISSN：2095-2546
出版年度：2020
页码：1-10
DOI：10.1016/j.jshs.2020.03.004
出版社：Elsevier
摘要：MicroRNAs (miRs) are small regulatory RNA transcripts capable of post-transcriptional silencing of mRNA messages by entering a cellular bimolecular apparatus called RNA-induced silencing complex. miRs are involved in the regulation of cellular processes producing, eliminating or repairing the damage caused by reactive oxygen species, and they are active players in redox homeostasis. Increased mitochondrial biogenesis, function and hypertrophy of skeletal muscle are important adaptive responses to regular exercise. In the present review, we highlight some of the redox-sensitive regulatory roles of miRs.
关键词：Adaptation; Exercise; MicroRNA; Oxidative damage; Reactive oxygen species; Redox regulation